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Fukuto et al , 2004)
The liver metabolizes most circulating melatonin via CYP1A2 (and partly CYP2C19), while cells themselves convert it to AFMK and AMK, metabolites known for potent antioxidant and anti-inflammatory activity (183)
Methycobal Injection helps replenish this deficiency
Mass spectrometry analysis of metabolitessample preparation The liver, brain, kidney, and lung tissues were homogenized with a pre-chilled BioPulverizer (59012MS, BioSpec) and then placed on dry ice
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